Metabolic dysfunction fatty liver disease (MAFLD), also called nonalcoholic fatty liver disease (NAFLD), has become increasingly common in the Western world, causing liver cirrhosis or hepatocellular carcinoma (HCC). The development of MAFLD is associated with mitochondrial dysfunction and stress. A very recent review – Mitochondrial Dysfunction in Metabolic Dysfunction Fatty Liver Disease (MAFLD) – summarizes the effects of several potential treatment strategies for MAFLD, including antioxidants, reagents, and intestinal microorganisms and metabolites.
We’re happy this work cites Mitologics reference published in 2017 in Environmental Toxicology (Wiley) – Chronic and low exposure to a pharmaceutical cocktail induces mitochondrial dysfunction in liver and hyperglycemia: Differential responses between lean and obese mice – by Mitologics and Inserm U-1317 (Bernard Fromenty) teams.
Dear colleagues from West China Hospital, thanks for your interest in our work!