MitoXpert®
LATEST NEWS
Mitologics is sponsor of the 3rd World Congress on Targeting Mitochondria and will present its screening assay on isolated liver mitochondria (MiToxView platform) predictive for hepatotoxicity risks in human.
(8/9 October 2012 - Berlin - Germany)


NEW PUBLICATION
Aftins Increase Amyloid-β42, Lower Amyloid-β38, and Do Not Alter Amyloid-β40 Extracellular Production in vitro: Toward a Chemical Model of Alzheimer's Disease?
Hochard A et al.
2013 - J Alzheimers Dis.

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48, Boulevard Sérurier
75019 PARIS
FRANCE



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Webmaster: Jérôme FLATOT
 
 
The MitoXpert platform allows to improve knowledge of compound mechanism on mitochondria or to see a protective effect against stress and damages.
Protection / Mechanistic studies
  • Calcic stress
    Targeting of the Permeability Transition Pore (PTP)
  • Potassic stress
    Targeting of the Mito-K ATP-dependent channel

  • Apoptotic stress
    Bax / Bak pores opening
  • Oxydative stress
    Targeting of Complexes I & III, MnSOD, GST